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Symbol
Name
ID 		Agt
angiotensinogen
MGI:87963
Phenotype annotations related to renal/urinary system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Urinary mulberry cells
Proteinuria
Lipiduria
Abnormality of the kidney
Renal insufficiency
Acute kidney injury
Chronic kidney disease
Disease(s) Associated with AGT
Fabry disease
pre-eclampsia

Mouse Phenotypes
renal/urinary system phenotype
abnormal kidney afferent arteriole morphology
abnormal kidney cortex artery morphology
abnormal kidney interlobular artery morphology
abnormal kidney vasculature morphology
increased renal plasma flow rate
increased kidney weight
decreased urine aldosterone level
increased urine antidiuretic hormone level
decreased urine potassium level
decreased urine sodium level
decreased urine osmolality
tubulointerstitial nephritis
abnormal kidney morphology
dilated kidney collecting duct
abnormal kidney cortex morphology
abnormal juxtaglomerular apparatus morphology
abnormal renal glomerulus morphology
expanded mesangial matrix
decreased renal glomerulus number
kidney cortex atrophy
renal interstitial fibrosis
abnormal kidney inner medulla morphology
kidney papillary atrophy
kidney papillary hypoplasia
kidney medulla atrophy
hydronephrosis
kidney atrophy
renal tubule atrophy
dilated renal tubule
abnormal renal/urinary system physiology
abnormal renal filtration rate
decreased creatinine clearance
increased urine flow rate
polyuria
Availability Mouse Genotype
Agttm1Afu/Agttm1Afu
Agttm1Ii/Agttm1Ii
Agttm1Unc/Agttm1Unc
Agttm1Unc/Agt+ *
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory